Cognitive-behavioral therapy seems to ramp up the beneficial effect of antidepressant treatment for children and teens. About 60 percent of youngsters will respond favorably to their first antidepressant medication — generally a selective serotonin reuptake inhibitor, UTMB’s Dr. Karen D. Wagner said at a psychopharmacology update held by the American Academy of Child and Adolescent Psychiatry. Switching to a different antidepressant will help about 50 percent of those who don’t respond. But adding psychotherapy will grab about 10 percent more — bringing the total response rate up to around 70 percent.